Slide background
Slide background




IARC Monographs Volume 129

ID 16131 | | Visite: 1910 | Documenti Chemicals EntiPermalink: https://www.certifico.com/id/16131

IARC Monographs Volume 129

IARC Monographs on the Identification of Carcinogenic Hazards to Humans Volume 129

Gentian Violet, Leucogentian Violet, Malachite Green, Leucomalachite Green, and CI Direct Blue 218

This volume of the IARC Monographs provides evaluations of the carcinogenicity of gentian violet, leucogentian violet, malachite green, leucomalachite green, and CI Direct Blue 218.

This volume of the IARC Monographs provides evaluations of the carcinogenicity of three dyes and their two leucometabolites: gentian violet, leucogentian violet, malachite green, leucomalachite green, and CI Direct Blue 218.

Gentian violet and malachite green are cationic triphenylmethane dyes widely used for textiles, paper, and acrylic products, as biological stains, and in some hair dyes and other cosmetics. Because of their antibacterial and antifungal properties, they have had various medical, veterinary, and aquaculture applications, including the treatment of livestock, animal feed, ornamental fish, and farmed fish and shellfish.

Leucogentian violet and leucomalachite green are used as precursors in the production of their parent compounds and have direct applications as chromogenic reagents in analytical chemistry and as radiochromic indicators in dosimeters.

CI Direct Blue 218 is a copper-chelated dimethoxybenzidine-based azo dye used for cellulose, acetate, nylon, silk, wool, tissue, fine papers, and textile goods.

For all agents, data were sparse regarding exposure levels, but indicated that exposures can occur in occupational settings and in the general population.

An IARC Monographs Working Group reviewed evidence from cancer bioassays in experimental animals and mechanistic studies to assess the carcinogenic hazard to humans of exposure to these agents and concluded that:

- Gentian violet, leucomalachite green, and CI Direct Blue 218 are possibly carcinogenic to humans (Group 2B)
- Leucogentian violet and malachite green are not classifiable as to their carcinogenicity to humans (Group 3).

...

Fonte: IARC

Collegati

Descrizione Livello Dimensione Downloads
Allegato riservato Volume129.pdf
 
7061 kB 7

Tags: Chemicals Abbonati Chemicals

Articoli correlati

Ultimi archiviati Chemicals

Lug 03, 2025 475

Regolamento (Euratom) 2021/765

Regolamento (Euratom) 2021/765 ID 24219 | 03.07.2025 Regolamento (Euratom) 2021/765 del Consiglio del 10 maggio 2021 che istituisce il programma di ricerca e formazione della Comunità europea dell'energia atomica per il periodo 2021-2025 che integra il programma quadro di ricerca e innovazione… Leggi tutto
Lug 03, 2025 484

Regolamento (Euratom) 2025/1304

 Regolamento (Euratom) 2025/1304 ID 24218 | 03.07.2025 Regolamento (Euratom) 2025/1304 del Consiglio, del 23 giugno 2025, che istituisce il programma di ricerca e formazione della Comunità europea dell’energia atomica per il periodo 2026-2027 che integra il programma quadro di ricerca e innovazione… Leggi tutto
ECHA compendium of analytical methods
Giu 27, 2025 752

ECHA compendium of analytical methods for enforcing REACH restrictions - Ed. 3.0 2025

ECHA compendium of analytical methods for enforcing REACH restrictions - Ed. 3.0 2025 ID 24178 | 27.06.2025 / Attached ECHA has updated its compendium of analytical methods to help authorities to enforce and companies to comply with REACH restrictions. The compendium consists of a collection of… Leggi tutto
ECHA 2025   Key Areas of Regulatory Challenge
Giu 11, 2025 911

ECHA 2025 - Key Areas of Regulatory Challenge

ECHA 2025 - Key Areas of Regulatory Challenge ID 24098 | 11.06.2025 / Attached The report introduces new topics to reflect ECHA’s growing responsibilities. It also covers emerging topics in waste and recycling that aim to support circularity and enhance Europe’s industrial competitiveness. For… Leggi tutto
REACH Authorisation List
Giu 09, 2025 889

REACH Authorisation Decisions List / Last update: 23.05.2025

REACH Authorisation Decisions List / Last update: 23.05.2025 ID 24091 | Last update: 09.06.2025 REACH Authorisation Decisions List of authorisation decisions adopted on the basis of Article 64 of Regulation (EC) No 1907/2006 (REACH). The list also includes reference to related documentation… Leggi tutto

Più letti Chemicals

Notifica HACCP
Apr 05, 2022 103593

Notifica ai fini registrazione Regolamento CE n. 852/2004

Notifica ai fini della registrazione (Reg. CE n. 852/2004) - Ex notifica sanitaria alimentare ID 7901 | 06.03.2019 / Modello notifica allegato [panel]Regolamento (CE) 852/2004...Articolo 6 Controlli ufficiali, registrazione e riconoscimento 1. Gli operatori del settore alimentare collaborano con le… Leggi tutto