Slide background
Slide background




IARC Monographs Volume 134

ID 21826 | | Visite: 886 | Documenti ChemicalsPermalink: https://www.certifico.com/id/21826

IARC Monographs Volume 134

IARC Monographs Volume 134 / Aspartame, methyleugenol, and isoeugenol

ID 21826 | 08.05.2024 / In allegato

This volume of the IARC Monographs provides evaluations of the carcinogenicity of three agents: aspartame, methyleugenol, and isoeugenol.

Aspartame is a low-calorie artificial sweetener that has been widely used in foods and beverages since the 1980s. Historically, artificially sweetened beverages have been the major source of exposure to aspartame, but to a lesser extent at present since aspartame is typically used in mixtures with other sweeteners. The highest concentrations of aspartame are found in tabletop sweeteners, chewing gums, and food supplements. Other sources include cosmetics and medicines.

Methyleugenol is a flavour and fragrance compound that occurs naturally in essential oils of various plants. It is used in cosmetics and personal care products and as an insect attractant. Although its use as a flavouring agent is prohibited in the European Union and the USA, it is still present in various foods and consumer products due to its natural occurrence in herbs and spices. The general population is ubiquitously exposed through the ingestion of food or use of personal care products.

Isoeugenol is a fragrance and flavour compound that occurs in many plant species and in wood smoke. It is used in food, cosmetics, household products, animal feed, and veterinary medicines. Firefighters and workers involved in isoeugenol synthesis or handling isoeugenol-containing products may be exposed.

An IARC Monographs Working Group reviewed evidence from epidemiological studies, cancer bioassays in experimental animals, and mechanistic studies to assess the carcinogenic hazard to humans of exposure to these agents and concluded that:

- Aspartame and isoeugenol are possibly carcinogenic to humans (Group 2B);
- Methyleugenol is probably carcinogenic to humans (Group 2A).

Collegati

DescrizioneLinguaDimensioneDownloads
Scarica questo file (IARC Monographs Volume 134.pdf)IARC Monographs Volume 134
IARC 2024
EN13136 kB130

Tags: Chemicals Agente chimico

Articoli correlati

Ultimi archiviati Chemicals

Regolamento di esecuzione  UE  2024 3121
Dic 17, 2024 65

Regolamento di esecuzione (UE) 2024/3121

Regolamento di esecuzione (UE) 2024/3121 ID 23137 | 17.12.2024 Regolamento di esecuzione (UE) 2024/3121 della Commissione, del 16 dicembre 2024, che modifica il regolamento di esecuzione (UE) 2021/1378 per quanto riguarda il riconoscimento, a norma dell’articolo 46 del regolamento (UE) 2018/848 del… Leggi tutto
Regolamento di esecuzione  UE  2021 1378
Dic 17, 2024 63

Regolamento di esecuzione (UE) 2021/1378

Regolamento di esecuzione (UE) 2021/1378 ID 23136 | 17.12.2024 Regolamento di esecuzione (UE) 2021/1378 della Commissione del 19 agosto 2021 che fissa determinate norme riguardanti il certificato rilasciato agli operatori, ai gruppi di operatori e agli esportatori di paesi terzi coinvolti nelle… Leggi tutto
Report on the exchange of information under the PIC Regulation in 2022 2023
Dic 12, 2024 81

Report on the exchange of information under the PIC Regulation in 2022-2023

Report on the exchange of information under the PIC Regulation in 2022-2023 ID 23101 | 12.12.2024 In 2022 and 2023, the Union transmitted 9 414 and 9 277 export notifications, respectively. These related to 113 PIC chemicals for exports to 153 non-EU countries in 2022, and 132 PIC chemicals for… Leggi tutto
Dic 09, 2024 87

Regolamento delegato (UE) 2024/3095

Regolamento delegato (UE) 2024/3095 ID 23077 | 09.12.2024 Regolamento delegato (UE) 2024/3095 della Commissione, del 29 luglio 2024, che modifica il regolamento delegato (UE) 2021/1698 per quanto riguarda la certificazione di determinati operatori e gruppi di operatori di paesi terzi e i controlli… Leggi tutto
REACH Authorisation List
Nov 25, 2024 249

REACH Authorisation Decisions List / Last update: 15.11.2024

REACH Authorisation Decisions List / Last update: 15.11.2024 ID 23004 | Last update: 15.11.2024 REACH Authorisation Decisions List of authorisation decisions adopted on the basis of Article 64 of Regulation (EC) No 1907/2006 (REACH). The list also includes reference to related documentation… Leggi tutto
Nov 18, 2024 353

Rettifica regolamento delegato 2023/707 - 18.11.2024

Rettifica regolamento delegato 2023/707 - 18.11.2024 ID 22953 | 18.11.2024 Rettifica del regolamento delegato 2023/707 della Commissione, del 19 dicembre 2022, che modifica il regolamento (CE) n. 1272/2008 per quanto riguarda i criteri e le classi di pericolo per la classificazione, l’etichettatura… Leggi tutto

Più letti Chemicals

Notifica HACCP
Apr 05, 2022 88114

Notifica ai fini registrazione Regolamento CE n. 852/2004

Notifica ai fini della registrazione (Reg. CE n. 852/2004) - Ex notifica sanitaria alimentare ID 7901 | 06.03.2019 / Modello notifica allegato [panel]Regolamento (CE) 852/2004...Articolo 6 Controlli ufficiali, registrazione e riconoscimento 1. Gli operatori del settore alimentare collaborano con le… Leggi tutto